Karam F A Soliman Selected Research

1-Methyl-4-phenylpyridinium (1 Methyl 4 phenylpyridinium)

5/2021	Metabolic Response to the Mitochondrial Toxin 1-Methyl-4-phenylpyridinium (MPP+) in LDH-A/B Double-knockout LS174T Colon Cancer Cells.
10/2014	Selective anticancer activity of neurotoxin 1-methyl-4-phenylpyridinium on non-small cell lung adenocarcinoma A549 cells.
9/2010	The protective role of D-glucose against 1-methyl-4-phenylpyridinium ion (MPP+): induced mitochondrial dysfunction in C6 astroglial cells.
6/2010	Evaluation of endogenous acidic metabolic products associated with carbohydrate metabolism in tumor cells.
1/2005	Lysophosphatidylcholine decreases locomotor activities and dopamine turnover rate in rats.
1/2005	Inhibitory effects of cigarette smoke on glial inducible nitric oxide synthase and lack of protective properties against oxidative neurotoxins in vitro.
3/2004	Effects of enhancing mitochondrial oxidative phosphorylation with reducing equivalents and ubiquinone on 1-methyl-4-phenylpyridinium toxicity and complex I-IV damage in neuroblastoma cells.
7/2003	Acetyl-L-carnitine cytoprotection against 1-methyl-4-phenylpyridinium toxicity in neuroblastoma cells.
1/2003	The role of glycolysis and gluconeogenesis in the cytoprotection of neuroblastoma cells against 1-methyl 4-phenylpyridinium ion toxicity.

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Karam F A Soliman Research Topics

Disease

32	Neoplasms (Cancer) 05/2022 - 03/2009
19	Parkinson Disease (Parkinson's Disease) 12/2021 - 08/2002
18	Triple Negative Breast Neoplasms 05/2022 - 01/2017
12	Neuroblastoma 01/2012 - 01/2003
10	Inflammation (Inflammations) 01/2022 - 05/2003
9	Neurodegenerative Diseases (Neurodegenerative Disease) 05/2022 - 05/2003
8	Breast Neoplasms (Breast Cancer) 07/2021 - 01/2015
8	Glioma (Gliomas) 01/2017 - 10/2002
6	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 05/2003
3	Neuroinflammatory Diseases 01/2022 - 01/2018
3	Carcinogenesis 12/2021 - 01/2019
2	Renal Cell Carcinoma (Grawitz Tumor) 05/2022 - 12/2021
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2022 - 09/2010
2	Adenocarcinoma of Lung 01/2022 - 10/2014
2	Carcinoma (Carcinomatosis) 12/2021 - 01/2017
2	Colonic Neoplasms (Colon Cancer) 05/2021 - 09/2020
2	Neoplasm Metastasis (Metastasis) 04/2021 - 11/2017
2	Prostatic Neoplasms (Prostate Cancer) 05/2020 - 01/2015
2	Parkinsonian Disorders (Parkinsonism) 06/2007 - 01/2005
1	Nervous System Diseases (Neurological Disorders) 12/2021

Drug/Important Bio-Agent (IBA)

13	Proteins (Proteins, Gene)FDA Link 05/2022 - 03/2004
11	CytokinesIBA 12/2021 - 03/2004
9	1-Methyl-4-phenylpyridinium (1 Methyl 4 phenylpyridinium)IBA 05/2021 - 01/2003
8	Lactic Acid (Lactate)FDA LinkGeneric 11/2021 - 06/2010
8	Glucose (Dextrose)FDA LinkGeneric 11/2021 - 03/2004
7	FlavonoidsIBA 05/2022 - 08/2019
7	AntioxidantsIBA 07/2020 - 02/2003
6	EnzymesIBA 09/2020 - 02/2003
6	Monoamine Oxidase (MAO)IBA 01/2017 - 05/2003
5	Oxidoreductases (Dehydrogenase)IBA 11/2021 - 01/2015
5	Hormones (Hormone)IBA 07/2021 - 01/2017
5	Interferon-gamma (Interferon, gamma)IBA 01/2017 - 10/2002
5	LipopolysaccharidesIBA 01/2017 - 10/2002
4	thymoquinoneIBA 05/2022 - 09/2015
4	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022 - 11/2002
4	Prostaglandins GIBA 11/2021 - 01/2015
4	PolyphenolsIBA 05/2021 - 08/2019
4	Lactate Dehydrogenase 5IBA 05/2021 - 01/2015
4	Biological ProductsIBA 01/2017 - 03/2004
4	NeurotoxinsIBA 10/2014 - 05/2003
4	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 01/2012 - 05/2003
3	Biomarkers (Surrogate Marker)IBA 05/2022 - 01/2015
3	Pharmaceutical PreparationsIBA 07/2021 - 03/2009
3	Adenosine Triphosphate (ATP)IBA 05/2021 - 06/2010
3	Monoamine Oxidase Inhibitors (Monoamine Oxidase Inhibitor)IBA 05/2020 - 01/2015
3	Pyruvic Acid (Pyruvate)IBA 06/2010 - 02/2003
3	Dopamine (Intropin)FDA LinkGeneric 07/2006 - 10/2002
3	S-Adenosylmethionine (Ademetionine)IBA 01/2005 - 03/2004
3	Oxidopamine (6 Hydroxydopamine)IBA 01/2005 - 02/2003
3	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 05/2003 - 10/2002
2	Neuroprotective AgentsIBA 05/2022 - 05/2016
2	ManganeseIBA 12/2021 - 03/2012
2	Messenger RNA (mRNA)IBA 11/2021 - 01/2020
2	MicroRNAs (MicroRNA)IBA 04/2021 - 01/2017
2	SynucleinsIBA 12/2020 - 01/2011
2	Estrogens (Estrogen)FDA Link 03/2020 - 11/2019
2	ApigeninIBA 03/2020 - 11/2019
2	ChemokinesIBA 01/2020 - 11/2019
2	GossypolIBA 01/2020 - 08/2019
2	trichostatin A (A 300)IBA 09/2018 - 01/2017
2	Histone Deacetylases (Histone Deacetylase)IBA 09/2018 - 01/2017
2	UbiquitinIBA 09/2018 - 01/2011
2	Histone Deacetylase InhibitorsIBA 09/2018 - 01/2017
2	Plant ExtractsIBA 05/2016 - 12/2010
2	Glutathione (Reduced Glutathione)IBA 09/2010 - 09/2009
2	AcidsIBA 06/2010 - 07/2006
2	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 03/2006 - 07/2003
2	Levodopa (L Dopa)FDA LinkGeneric 06/2005 - 11/2002
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 03/2004 - 11/2002
1	hesperetinIBA 05/2022
1	Peptides (Polypeptides)IBA 01/2022
1	PlatinumIBA 01/2022
1	Amyloid beta-PeptidesIBA 01/2022
1	epigallocatechin gallate (epigallocatechin-3-gallate)IBA 01/2022
1	ElementsIBA 12/2021
1	RE1-silencing transcription factorIBA 12/2021
1	diallyl trisulfideIBA 12/2021
1	IsoenzymesIBA 11/2021
1	SaponinsIBA 11/2021
1	LigandsIBA 11/2021
1	wye (Y base)IBA 11/2021
1	LipidsIBA 11/2021
1	Detergents (Detergent)IBA 11/2021
1	Paclitaxel (Taxol)FDA LinkGeneric 07/2021
1	1,2,3,4-tetrahydroisoquinolineIBA 07/2021
1	GM-4-53IBA 07/2021
1	Cytostatic AgentsIBA 07/2021
1	Antineoplastic Agents (Antineoplastics)IBA 05/2021
1	amsonic acid (DAS)IBA 01/2021
1	Benzo(a)pyreneIBA 01/2021
1	DNA (Deoxyribonucleic Acid)IBA 01/2021
1	allyl sulfideIBA 01/2021
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 12/2020
1	oleuropeinIBA 12/2020
1	Olive OilIBA 12/2020
1	CaspasesIBA 12/2020

Therapy/Procedure

10	Drug Therapy (Chemotherapy) 01/2022 - 03/2009
7	Therapeutics 11/2021 - 03/2015
1	Molecular Targeted Therapy 01/2022
1	Mediterranean Diet 12/2020